Jessner Lymphocytic Infiltrate |
The cause of Jessner lymphocytic infiltration of the skin is currently unknown although there are some proposed theories. Some studies indicate an association with the bacteria, Borrelia, while other data suggest that photosensitivity can be the cause. Some believe that this condition is a variant of lupus erythematosus.
A thorough medical history is warranted due to the possible hereditary nature of this condition and also due to the association of the onset of lesions after sun exposure. Workup may include provocative phototesting which is when ultraviolet A and B radiation is used to elicit lesions which can lead to better guidance to treatment. A skin biopsy on a relatively new lesion may be needed to confirm the diagnosis and to rule out other similar conditions such as discoid lupus erythematosus and polymorphous light eruption. Some lab tests that may be considered to rule out other causes include a CBC, ANA, ESR, and anti-Ro and anti-La autoantibodies. Treatment may not be warranted as the skin lesions may resolve spontaneously. For others, treatment options include excision of small lesions, cryotherapy, lasers, photodynamic therapy, topical steroids, intralesional steroids, systemic steroids, and some medications such as thalidomide and methotrexate. Antimalarials such as hydroxychloroquine have been shown to help lesions that are associated with photosensitivity. Cosmetic camouflage may be used to improve appearance. Sun avoidance and photoprotection is important to prevent worsening or new lesions. Regular follow up with a dermatologist is strongly recommended to monitor progress and treatment.
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2/27/2018MACRA/MIPS Update
10/12/2017Foundation for Osteopathic Dermatology
7/6/2016Disclosure to members regarding CME activities
4/3/2014The Burning Truth
12/19/2013Osteopathic Training Statement
10/9/2018 » 10/13/2018
2018 AOCD Fall Current Concepts in Dermatology Meeting
4/9/2019 » 4/13/2019
2019 AOCD Spring Current Concepts in Dermatology Meeting
9/24/2019 » 9/28/2019
2019 AOCD Fall Current Concepts in Dermatology
2/19/2020 » 2/22/2020
2020 AOCD Spring Current Concepts in Dermatology
2/24/2021 » 2/27/2021
2021 AOCD Spring Current Concepts in Dermatology